Dr. Hou and others from the Immunology Department of Shandong Academy of Medical Sciences in China had 28 patients with chronic renal insufficiency take 3-5 g of Cordyceps extract twice daily for 30 minutes with boiling water, and provided high-quality, low-protein food for meals. The dynamics were observed for 10-12 months, and the concentrations of T-lymphocyte subgroup, hemoglobin, albumin, urea nitrogen (BUN), and chromium were measured. As a result, the T-lymphocyte subgroup of patients with renal impairment was decreased compared to normal subjects, which means that the cellular immune function of patients with renal impairment was significantly lower. In general, patients with weakened kidney function are easily infected with pathogens, and according to clinical statistics in China, more than 80% die without active treatment. Several scholars say that the reason is due to decreased immune function. However, in patients taking Cordyceps, the cellular immune function was significantly improved (P≤0.05), and serum albumin and hemoglobin also increased. In the end, Dr. Hou et al. concluded that the administration of Cordyceps(a drug in China) protects and restores renal function and has no side effects in a situation in which chronically weakened patients consume high-cost, low-protein foods and receive general public treatment. Since this study is the result of a clinical trial conducted on humans, it seems highly reliable.
On the other hand, it was found that Cordyceps has a protective effect on renal toxicity in elderly patients. Dr. Zheng’s research team at Nanjing Military General Hospital in China randomly divided 21 hospitalized elderly patients into two groups, and then took 0.2 g of antibiotic amikacin sulfate twice a day for 6 days. Afterward, group A was fed with Cordyceps, and group B was fed with a placebo made from glucose. Then, as a result of measuring urine nephroaminoglycosidase and β-microglobulin, the activity was lower in group A than in group B. These two enzymes are indicator enzymes that show renal toxicity when taking drugs such as antibiotics, and their activity increases when renal toxicity occurs. Amikacin sulfate is widely used as one of the effective antibiotics commonly used in China, but its use is being suppressed as the problem of renal toxicity has emerged. However, when amikacin sulfate was administered to elderly patients who needed antibiotics and Cordyceps was fed together, the activity of these enzymes initially increased and then immediately decreased, suggesting that Cordyceps has a protective effect on the renal toxicity caused by antibiotics in elderly patients. means to indicate This study also appears to be quite reliable as it is the result of a clinical trial directly on humans.
Zhu and Liu, MD, from the Shanghai Institute of Chinese Medicine in Shanghai, China, hospitalized all 85 patients with cirrhosis after the onset of hepatitis. For the 60 patients in the treatment group, 4.5 g of Cordyceps mycelium capsules were taken 3 times a day, and the extract was administered intravenously. Injected, 25 others were treated with intravenous glucose injection for 3 months. It was announced that the cellular immune function of the treatment group was significantly improved after treatment, the lymph node conversion rate and immune cells were greatly increased, the NK cell activity was improved, and the immune protein was significantly increased. From these results, the same research team argued that Cordyceps and Doin extract was a green light for improving liver function, suppressing, and alleviating disease exacerbations.